Borussia Dortmund – Tottenham 3-0 (Aubameyang 30, Reus 60, 70)
FC Basel – Sevilla 0-0
Fenerbahce – Braga 1-0 (Topal 83)
Şahtior – Anderlecht 3-1 (Taison 22, Kucher 24, Alves da Silva / Acheampong)
Bilbao – Valencia 1-0 (Garcia 20)
Liverpool – Manchester United 2-0 (Sturridge pen. 20, Firmino 74)
Sparta Praga – Lazio 1-1 (Frydek 13 / Parolo 39)
Villarreal – Leverkusen 2-0 (Bakambu 4, Bakambu 56)